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Search Results for " pf_5274857_mseylate_(1373615_35_0_free_base) "

1

Compounds

Cat No. Product Name Synonyms Targets
T28388 PF-5274857 mseylate (1373615-35-0 free base) PF5274857 HCl , PF 5274857 , PF-5274857 , PF-5274857 mesylate , PF-5274857 mseylate
PF-5274857 is a potent, orally active and selective inhibitor of hedgehog (Hh) signaling pathway (IC50 = 5.8 nM, Ki = 4.6 nM) . PF-5274857 effectively penetrates the blood-brain barrier and inhibits Smo activity in the b...
TargetMol