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PF-06882961 Tris

Catalog No. T8876 CAS 2230198-03-3

Synonyms: UNII-2HJV78O0SS

PF-06882961 Tris (UNII-2HJV78O0SS) is an orally bioavailable glucagon-like peptide-1 receptor (GLP-1R) agonist.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

PF-06882961 Tris, CAS 2230198-03-3

Pack Size	Availability	Price/USD
1 mg	In stock	$ 133.00
5 mg	In stock	$ 302.00
10 mg	In stock	$ 453.00
25 mg	In stock	$ 747.00
50 mg	In stock	$ 1,050.00
100 mg	In stock	$ 1,420.00
500 mg	In stock	$ 2,830.00

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Purity: 99.52%

Purity: 98.11%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	PF-06882961 Tris (UNII-2HJV78O0SS) is an orally bioavailable glucagon-like peptide-1 receptor (GLP-1R) agonist.
In vitro	Biological in-vitro testing revealed favorable ADME and pharmacological profiles for the best PF-06882961 Tris[1].
In vivo	PF-06882961 Tris shows mild to moderate damage to the heart, moderate to severe effects on the thymus gland (which helps with managing infection), mild to moderate stomach ulcers at the highest dose level given in the rat[2].

Synonyms	UNII-2HJV78O0SS
Molecular Weight	676.7
Formula	C35H41FN6O7
CAS No.	2230198-03-3

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 10 mM

References and Literature

1. Méndez M, Matter H, Defossa E, et al. Design, Synthesis, and Pharmacological Evaluation of Potent Positive Allosteric Modulators of the Glucagon-like Peptide-1 Receptor (GLP-1R). J Med Chem. 2020;63(5):2292-2307. doi:10.1021/acs.jmedchem.9b01071 2. POSSIBLE SIDE EFFECTS AND RISKS OF THE STUDY DRUG AND PROCEDURES.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Drug Library Drug Repurposing Compound Library GPCR Compound Library Anti-Cancer Clinical Compound Library Orally Active Compound Library NO PAINS Compound Library Bioactive Compound Library Anti-Diabetic Compound Library Clinical Compound Library Anti-Obesity Compound Library

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Related compounds with same targets

L-168049 3-Deoxyglucosone Glucagon (1-29), bovine, human, porcine hydrochloride GLP-1R modulator C5 Shanzhiside methyl ester Lotiglipron Semaglutide Mazdutide acetate（2259884-03-0 free base）

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

PF-06882961 Tris 2230198-03-3 GPCR/G Protein Glucagon Receptor PF 06882961 Tris UNII-2HJV78O0SS PF06882961 Tris inhibitor inhibit

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