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Ocaphane Hydrochloride

Catalog No. T26365L CAS 2185-98-0

Synonyms: AT 581, AT-581, AT581, Ocaphane HCl

Ocaphane Hydrochloride is a strong antitumor agent used on a number of animal tumors.

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Ocaphane Hydrochloride Chemical Structure

Ocaphane Hydrochloride, CAS 2185-98-0

Pack Size	Availability	Price/USD
25 mg	6-8 weeks	$ 1,520.00
50 mg	6-8 weeks	$ 1,980.00
100 mg	6-8 weeks	$ 2,500.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Ocaphane Hydrochloride is a strong antitumor agent used on a number of animal tumors.

Synonyms	AT 581, AT-581, AT581, Ocaphane HCl
Molecular Weight	392.14
Formula	C14H22Cl4N2O2
CAS No.	2185-98-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Su-yin C, Hsiu-fang Y, Pin H. Absorption, distribution and excretion of C14-AT-581 in animals. Chin Med J (Engl). 1976 Nov;2(6):441-4. PubMed PMID: 828876. 2. Yang JL, Lu FL, Wang LJ, Xu B. [The therapeutic effect of O-[bis-(2-chloroethyl)-aminomethyl]-phenylalanine dihydrochloride (ocaphane, AT-581) on intracerebral growth of Brown-Pearce carcinoma in rabbits (author's transl)]. Yao Xue Xue Bao. 1981 Dec;16(12):881-5. Chinese. PubMed PMID: 7340381. 3. Yang JL, Hsu B. [Studies on the combined chemotherapy of o-[bis-(2-chloroethyl)-aminomethyl]-phenylalanine dihydrochloride (AT-581) and operation in the treatment of Brown-Pearce carcinoma in the rabbit]. Yao Xue Xue Bao. 1966 Feb;13(2):113-8. Chinese. PubMed PMID: 5952402. 4. YANG JL, HSU B. [THERAPEUTIC EFFECT OF AT-581 ON THE BROWN-PEARCE CARCINOMA IN RABBITS AND ITS INFLUENCE ON MITOSIS OF THE TUMOR CELLS]. Yao Xue Xue Bao. 1965 Apr;12:235-41. Chinese. PubMed PMID: 14321745.

Dose Conversion

You can also refer to dose conversion for different animals. More

In vivo Formulation Calculator (Clear solution)

Step One: Enter information below

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Step Two: Enter the in vivo formulation

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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Molarity Calculator

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Molecular Weight Calculator

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
Enter 10 into the Concentration box and select the correct unit (millimolar)
Enter 10 into the Volume box and select the correct unit (milliliter)
Press calculate
The answer of 19.713 mg appears in the Mass box

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Calculator the dilution required to prepare a stock solution

Calculate the dilution required to prepare a stock solution
The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
Enter 50 into the Concentration (final) box and select the correct unit (micromolar)
Enter 20 into the Volume (final) box and select the correct unit (milliliter)
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Molecule Formula

Molecular Weight g/mol

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Tip: Chemical formula is case sensitive: C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:
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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Ocaphane Hydrochloride 2185-98-0 AT 581 AT-581 AT581 Ocaphane HCl inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.