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PI-091

Catalog No. T28412 CAS 129051-63-4

PI-091 inhibits platelet aggregation.

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PI-091, CAS 129051-63-4

Pack Size	Availability	Price/USD	Quantity
25 mg	6-8 weeks	$ 1,520.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description

PI-091 inhibits platelet aggregation.

Molecular Weight	311.42
Formula	C17H29NO4
CAS No.	129051-63-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Uchiro H, Shionozaki N, Kobayakawa Y, Nakagawa H, Makino K. A novel convergent method for the synthesis of α-acyl-γ-hydroxylactams and its application in the total synthesis of PI-090 and 091. Bioorg Med Chem Lett. 2012 Jul 15;22(14):4765-8. doi: 10.1016/j.bmcl.2012.05.065. Epub 2012 May 24. PubMed PMID: 22704239. 2. Clark AJ, Dell CP, McDonagh JM, Geden J, Mawdsley P. Oxidative 5-endo cyclization of enamides mediated by ceric ammonium nitrate. Org Lett. 2003 Jun 12;5(12):2063-6. PubMed PMID: 12790529. 3. Iwasawa N, Maeyama K. A Highly Efficient Synthesis of (-)-PI-091 Construction of the 4-Alkoxy-2-butene-4-lactam Skeleton from Fischer-Type Carbene Complexes, Alkynyllithiums, and Tosyl Isocyanate. J Org Chem. 1997 Apr 4;62(7):1918-1919. PubMed PMID: 11671489. 4. Shiraki R, Sumino A, Tadano Ki KI, Ogawa S. Total Synthesis of Natural PI-091, a New Platelet Aggregation Inhibitor of Microbial Origin. J Org Chem. 1996 Apr 19;61(8):2845-2852. PubMed PMID: 11667121.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

PI-091 129051-63-4 PI091 PI 091 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.