Powder: -20°C for 3 years | In solvent: -80°C for 1 year
OTS186935 trihydrochloride is a protein methyltransferase inhibitor of SUV39H2(IC50 of 6.49 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | OTS186935 trihydrochloride is a protein methyltransferase inhibitor of SUV39H2(IC50 of 6.49 nM). |
Targets&IC50 | SUV39H2:6.49 nM |
In vitro | OTS186935 trihydrochloride, revealed significant inhibition of tumor growth in mouse xenograft models using MDA-MB-231 breast cancer cells and A549 lung cancer cells without any detectable toxicity.??SUV39H2 inhibitors sensitize cancer cells to DOX by reduction of γ-H2AX levels in cancer cells |
In vivo | OTS186935 trihydrochloride?exhibits growth suppressive effects in human cancer cell line derived xenograft models[1]. |
Molecular Weight | 573.34 |
Formula | C25H29Cl4N5O2 |
CAS No. | 2093401-85-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
OTS186935 trihydrochloride 2093401-85-3 Others OTS 186935 OTS-186935 Trihydrochloride OTS 186935 Trihydrochloride OTS186935 Trihydrochloride OTS186935 OTS-186935 trihydrochloride OTS-186935 inhibitor inhibit