Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Nisoxetine, a potent and selective noradrenaline transporter (NET) inhibitor with a dissociation constant (Kd) of 0.76 nM, serves as an antidepressant and exhibits local anesthetic properties by blocking voltage-gated sodium channels.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | Inquiry | |
50 mg | 6-8 weeks | Inquiry | |
100 mg | 6-8 weeks | Inquiry |
Description | Nisoxetine, a potent and selective noradrenaline transporter (NET) inhibitor with a dissociation constant (Kd) of 0.76 nM, serves as an antidepressant and exhibits local anesthetic properties by blocking voltage-gated sodium channels. |
In vitro |
HyT36 (10 µ M ; 24 h) reduced the expression of GFP-HaloTag2/Fz4-HaloTag2/GFP-HaloTag7 fusion protein in HEK293 cells.[1] HyT36 (10 µ M ; 2 or 48 h) reduced the expression of EGFP in HEK293 Flp-In cells expressing HA-EGFP-HaloTag2 and enhanced the binding of Hsp70 to the HA-EGFP-HaloTag2 fusion protein.[3] HyT36 (50 nM ; 24 h) reduced the content of EGFP HaloTag2 in HEK293 Flp In cells expressing HA-EGFP HaloTag2.[3] HyT36 (1 µ M ; 4 d) reduced the expression of HA HaloTag2 HRasG12V in NIH-3T3 cells expressing HA HaloTag2 HRasG12V.[3] |
Molecular Weight | 271.35 |
Formula | C17H21NO2 |
CAS No. | 53179-07-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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Nisoxetine 53179-07-0 inhibitor inhibit