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NHE3-IN-1

Name: NHE3-IN-1
Brand: TargetMol
SKU: T12219
Price: 51 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T12219Cas No. 632355-68-1

NHE3-IN-1 is a inhibitor of Na+/H+-exchanger 3 (NHE-3).

NHE3-IN-1

🥰Excellent

Purity: 99.93%

Catalog No. T12219Cas No. 632355-68-1

NHE3-IN-1 is a inhibitor of Na+/H+-exchanger 3 (NHE-3).

Pack Size	Price	Availability	Quantity
25 mg	$51	In Stock
50 mg	$85	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.93%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description

NHE3-IN-1 is a inhibitor of Na+/H+-exchanger 3 (NHE-3).

Chemical Properties

Molecular Weight	263.75
Formula	C₁₂H₁₀ClN₃S
Cas No.	632355-68-1
Smiles	N(C=1C(C)=CSC1Cl)C=2NC=3C(N2)=CC=CC3
Relative Density.	1.474 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (189.57 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.7915 mL	18.9573 mL	37.9147 mL	189.5735 mL
5 mM	0.7583 mL	3.7915 mL	7.5829 mL	37.9147 mL
10 mM	0.3791 mL	1.8957 mL	3.7915 mL	18.9573 mL
20 mM	0.1896 mL	0.9479 mL	1.8957 mL	9.4787 mL
50 mM	0.0758 mL	0.3791 mL	0.7583 mL	3.7915 mL
100 mM	0.0379 mL	0.1896 mL	0.3791 mL	1.8957 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc