Powder: -20°C for 3 years | In solvent: -80°C for 1 year
N-Acetyl lysyltyrosylcysteine amide acetate is an effective and selective tripeptide inhibitor of myeloperoxidase (MPO). N-Acetyl lysyltyrosylcysteine amide acetate inhibits MPO-dependent hypochlorous acid (HOCl) generation, protein nitration, and LDL ox
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | Inquiry | $ 86.00 | |
5 mg | Inquiry | $ 197.00 | |
10 mg | Inquiry | $ 347.00 | |
25 mg | Inquiry | $ 625.00 | |
50 mg | Inquiry | $ 937.00 | |
100 mg | Inquiry | $ 1,397.00 | |
200 mg | Inquiry | $ 2,112.00 |
Description | N-Acetyl lysyltyrosylcysteine amide acetate is an effective and selective tripeptide inhibitor of myeloperoxidase (MPO). N-Acetyl lysyltyrosylcysteine amide acetate inhibits MPO-dependent hypochlorous acid (HOCl) generation, protein nitration, and LDL ox |
In vivo | N-Acetyl lysyltyrosylcysteine amide acetate (10 mg/kg; i.p.; daily 7 days) significantly protects BBB function and decreased neutrophil infiltration. N-Acetyl lysyltyrosylcysteine amide acetate (10 mg/kg; i.p.; daily 7 days) significantly reduces microglia/macrophage activation and neuron loss in MCAO mice. N-Acetyl lysyltyrosylcysteine amide acetate (10 mg/kg; i.p.; daily for 3-7 days) decreases apoptosis and cell injury in the brains of MCAO mice. N-Acetyl lysyltyrosylcysteine amide acetate reduced MPO in the brains of MCAO mice. N-Acetyl lysyltyrosylcysteine amide acetate reduces NO2Tyr and 4-HNE in MCAO mice. N-Acetyl lysyltyrosylcysteine amide acetate significantly decreases infarct size, blood-brain barrier leakage, infiltration of myeloid cells, loss of neurons, and apoptosis in the brains of middle cerebral artery occlusion (MCAO) mice. N-Acetyl lysyltyrosylcysteine amide acetate (10 mg/kg; i.p.; daily for 3-7 days) significantly reduces neurological severity scores and infarct size in MCAO mice[2]. |
Synonyms | N-Acetyl lysyltyrosylcysteine amide acetate(1287585-40-3 Free base) |
Molecular Weight | 513.61 |
Formula | C22H35N5O7S |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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N-Acetyl lysyltyrosylcysteine amide acetate Metabolism Glutathione Peroxidase N-Acetyl lysyltyrosylcysteine amide acetate(1287585-40-3 Free base) NAcetyl lysyltyrosylcysteine amide acetate N-Acetyl lysyltyrosylcysteine amide Acetate N Acetyl lysyltyrosylcysteine amide acetate inhibitor inhibit