Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Mapracorat is a novel non-steroidal selective agonist of glucocorticoid receptor.
Description | Mapracorat is a novel non-steroidal selective agonist of glucocorticoid receptor. |
In vitro | Mapracorat concentration-dependently inhibited TNFα secretion from activated canine PBMC (IC50: approximately 0.2 nM). |
In vivo | Intradermal injection of compound 48/80 (50 μg in 50 μL saline) caused a clear wheal and flare reaction over the 60 min observation period. Compared to a vehicle (acetone) treated areas, topical pre-treatment with mapracorat (0.1%) induces a significant reduction in the wheal and flare responses. |
Synonyms | BOL-303242X, ZK-245186 |
Molecular Weight | 462.48 |
Formula | C25H26F4N2O2 |
CAS No. | 887375-26-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 33.6 mg/mL (72.65 mM)
You can also refer to dose conversion for different animals. More
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Mapracorat 887375-26-0 Others BOL-303242X ZK 245186 ZK-245186 ZK245186 inhibitor inhibit