Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Linderone A shows anticancer activity against A549 non-small cell lung cancer cells and PC-3 prostate adenocarcinoma cell line.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | Inquiry | $ 798.00 | |
1 mL * 10 mM (in DMSO) | Inquiry | $ 1,268.00 |
Description | Linderone A shows anticancer activity against A549 non-small cell lung cancer cells and PC-3 prostate adenocarcinoma cell line. |
In vitro | Extensive spectroscopic analysis including 1D and 2D-NMR spectra determined their sturctures. In addition, the antioxidant activity of all the compounds has been determined using 2, 2-diphenyl-1-picrylhydrazyl radical scavenging (DPPH), ferric reducing antioxidant power (FRAP) and ferrous ion chelating (FIC) methods. Compound 3 showed excellent DPPH scavenging activity with IC50% value of 8.5 ± 0.004% (μg/mL) which is comparable with vitamin C. This compound, also showed an absorbance value of 1.00 ± 0.06% through FRAP test when compared with Butyl Hydroxy Aniline (BHA). However, FIC showed low activity for all the isolated compounds (chelating activity less than 50%) in comparison with ethylene diamine tetra acetic acid (EDTA). Anticancer activity for all compounds has also been measured on A375 human melanoma, HT-29 colon adenocarcinoma, MCF-7 human breast adenocarcinoma cells, WRL-68 normal hepatic cells, A549 non-small cell lung cancer cells and PC-3 prostate adenocarcinoma cell line[1] |
Source |
Molecular Weight | 286.28 |
Formula | C16H14O5 |
CAS No. | 1782-79-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Linderone 1782-79-2 Others inhibitor inhibit