Powder: -20°C for 3 years | In solvent: -80°C for 1 year
LTβR-IN-1 is a potent and selective lymphin β receptor (LTβR) inhibitor. LTβR-IN-1 has a selective inhibitory effect on the nuclear translocation of p52 of TNF12A, and has no obvious effect on the nuclear translocation of p65 mediated by TNF-α receptor, but inhibits the nuclear translocation of p52 stimulated by TWEAK or Anti-LTβR. Translocation with IC50 of 10 μM. LTβR-IN-1 regulates the NF-kB signaling pathway through a ligand-independent manner.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 51.00 | |
5 mg | In stock | $ 122.00 | |
10 mg | In stock | $ 197.00 | |
25 mg | In stock | $ 387.00 | |
50 mg | In stock | $ 576.00 | |
100 mg | In stock | $ 823.00 | |
500 mg | In stock | $ 1,680.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 133.00 |
Description | LTβR-IN-1 is a potent and selective lymphin β receptor (LTβR) inhibitor. LTβR-IN-1 has a selective inhibitory effect on the nuclear translocation of p52 of TNF12A, and has no obvious effect on the nuclear translocation of p65 mediated by TNF-α receptor, but inhibits the nuclear translocation of p52 stimulated by TWEAK or Anti-LTβR. Translocation with IC50 of 10 μM. LTβR-IN-1 regulates the NF-kB signaling pathway through a ligand-independent manner. |
Targets&IC50 | LTβR (p52 translocation):10 μM , LTβR (p52 translocation):0.169 μM |
Molecular Weight | 320.35 |
Formula | C18H16N4O2 |
CAS No. | 2189366-77-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 113 mg/mL (350 mM), Sonification is recommended.
You can also refer to dose conversion for different animals. More
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LTβR-IN-1 2189366-77-4 Immunology/Inflammation NF-Κb Others NF-κB LTR LTβR IN 1 LTbetaR-IN-1 LTbR-IN-1 LTβRIN1 inhibitor inhibit