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LDN-192960

LDN-192960
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Purity:99.32%
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LDN-192960

Catalog No. TQ0111Cas No. 184582-62-5
LDN-192960 is a potent inhibitor of Haspin and DYRK2 (IC50s: 10 nM and 48 nM).
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
1 mg$133In Stock
5 mg$163In Stock
10 mg$263In Stock
25 mg$528In Stock
50 mg$769In Stock
100 mg$1,080In Stock
500 mg$2,160In Stock
1 mL x 10 mM (in DMSO)$178In Stock
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Product Introduction

Bioactivity
Description
LDN-192960 is a potent inhibitor of Haspin and DYRK2 (IC50s: 10 nM and 48 nM).
Chemical Properties
Molecular Weight328.43
FormulaC18H20N2O2S
Cas No.184582-62-5
Storage & Solubility Information
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 30 mg/mL (91.34 mM)
MeOH: 1mg/mL(3.04mM)
Solution Preparation Table
DMSO/MeOH
1mg5mg10mg50mg
1 mM3.0448 mL15.2239 mL30.4479 mL152.2394 mL
DMSO
1mg5mg10mg50mg
5 mM0.6090 mL3.0448 mL6.0896 mL30.4479 mL
10 mM0.3045 mL1.5224 mL3.0448 mL15.2239 mL
20 mM0.1522 mL0.7612 mL1.5224 mL7.6120 mL
50 mM0.0609 mL0.3045 mL0.6090 mL3.0448 mL
100 mM0.0304 mL0.1522 mL0.3045 mL1.5224 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg, each TargetMol | Animal experiments animal weighs 20 g, and the dosage volume is 100 μL. A total of TargetMol | Animal experiments 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL.
Mother liquor preparation method: 2 mg of drug dissolved in 50 μLDMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μLDMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μLTween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify.
1 Enter information below:
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2 Enter the in vivo formulation:
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