Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Kelatorphan is an enkephalin degrading enzyme full inhibitor.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 8-10 weeks | $ 1,820.00 | |
50 mg | 8-10 weeks | $ 2,380.00 | |
100 mg | 8-10 weeks | $ 3,100.00 |
Description | Kelatorphan is an enkephalin degrading enzyme full inhibitor. |
In vivo | Kelatorphan (20 mg/kg i.v.) increases ventilation and there is no obvious difference between arthritic and non-arthritic rats, in arthritic rats. A slight (116%) but significant increase of respiration is also produced by Kelatorphan (20 mg/kg, n=6) 10±15 min after administration, in pentobarbital-anesthetized rats. Kelatorphan (10±20 mg/kg i.v.) increases minute-volume, in normal awake rats. The increase in ventilation is due to a dose-dependent increase in breathing frequency. The administration of Kelatorphan alone (50 μg) could cause a strong enhance of intact [3H]enkephalin content corresponding to 80±11% of total recovered radioactivity[2]. The effects of Kelatorphan are not antagonized by pretreatment with a small dose of naloxone (0.2 mg/kg i.v., 15 min before Kelatorphan), but a larger dose (1 mg/kg) significantly antagonized Kelatorphan (20 mg/kg) at 5 and 10 min in awake rats[3]. |
Molecular Weight | 294.3 |
Formula | C14H18N2O5 |
CAS No. | 92175-57-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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Kelatorphan 92175-57-0 Others inhibitor inhibit