Powder: -20°C for 3 years | In solvent: -80°C for 1 year
K34c is a potent and selective α5β1 integrin inhibitor (IC50 = 3.1 nM). K34c inhibits cell survival and migration, inhibits p53-dependent senescence induced by Temozolomide or Ellipticine and promotes apoptosis in U87MG cells. K34c also prevents TGFβ-induced infiltrationin vivoand reduces cell adhesion on fibronectin.
Description | K34c is a potent and selective α5β1 integrin inhibitor (IC50 = 3.1 nM). K34c inhibits cell survival and migration, inhibits p53-dependent senescence induced by Temozolomide or Ellipticine and promotes apoptosis in U87MG cells. K34c also prevents TGFβ-induced infiltrationin vivoand reduces cell adhesion on fibronectin. |
Molecular Weight | 447.53 |
Formula | C26H29N3O4 |
CAS No. | 939769-93-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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K34c 939769-93-4 K-34c inhibitor inhibit