Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ipragliflozin is a highly potent and selective SGLT2 inhibitor with an IC50 of 2.8 nM; little and NO potency for SGLT1/3/4/5/6.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 mg | 5 days | $ 30.00 |
Description | Ipragliflozin is a highly potent and selective SGLT2 inhibitor with an IC50 of 2.8 nM; little and NO potency for SGLT1/3/4/5/6. |
Targets&IC50 | SGLT2:2.8 nM |
In vitro | Ipragliflozin selectively and potently inhibits human, rat, and mouse SGLT2 at nanomolar ranges and exhibits stability against intestinal glucosidases. |
In vivo | Following oral administration, ipragliflozin demonstrates favorable pharmacokinetic properties and dose-dependently enhances urinary glucose excretion, with effects lasting over 12 hours in normal mice. This increase in urinary glucose excretion is significant at doses of 0.3 mg/kg or higher. Additionally, a single dose of ipragliflozin effectively increases urinary glucose excretion, lowers blood glucose and plasma insulin levels, and ameliorates glucose intolerance. |
Synonyms | Ipragliflozin L-Proline |
Molecular Weight | 519.58 |
Formula | C26H30FNO7S |
CAS No. | 951382-34-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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Ipragliflozin (L-Proline) 951382-34-6 Others Ipragliflozin (L Proline) Ipragliflozin (LProline) Ipragliflozin L-Proline Ipragliflozin L-Proline inhibitor inhibit