Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Idroxioleic acid ((R)-2-Hydroxyoleic acid; (R)-2-OHOA) is the R enantiomer of (Rac)-Idroxioleic acid. It is an orally active fatty acid known for its ability to modulate the lipid composition and structure of membranes. With demonstrated antitumor activities, Idroxioleic acid plays a significant role in the field of cancer research.
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25 mg | Inquiry | $ 1,520.00 |
Description | Idroxioleic acid ((R)-2-Hydroxyoleic acid; (R)-2-OHOA) is the R enantiomer of (Rac)-Idroxioleic acid. It is an orally active fatty acid known for its ability to modulate the lipid composition and structure of membranes. With demonstrated antitumor activities, Idroxioleic acid plays a significant role in the field of cancer research. |
In vitro | (R)-2-Hydroxyoleic acid ((R)-2-OHOA), also known as idroxioleic acid, effectively inhibited the growth of the A549 lung adenocarcinoma cell line, demonstrating an IC50 value of 252 μM[1]. |
In vivo | (R)-2-Hydroxyoleic acid (R)-2-OHOA, administered orally at a dosage of 400 mg/kg daily for 21 days, led to a 20-25% decrease in tumor volume[1]. This outcome was observed in a study involving male NUDE (Swiss) Crl:NU(Ico)-Foxn1nu mice, aged 5 weeks and weighing 30-35 g, which were injected with A549 human lung cancer cells[1]. |
Synonyms | (R)-2-Hydroxyoleic acid, (R)-2-OHOA |
Molecular Weight | 298.467 |
Formula | C18H34O3 |
CAS No. | 182370-45-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Idroxioleic acid 182370-45-2 (R)-2-Hydroxyoleic acid 2-OHOA (R)-2-OHOA 2-Hydroxyoleic acid inhibitor inhibit