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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T15550 | IDH-305 | Dehydrogenase | |
IDH-305 is an orally available, mutant-selective and brain-penetrant IDH1 inhibitor. IDH-305 shows greater than 200 fold selectivity for mutant IDH1 isoforms vs. WT (IC50s: 27 nM (IDH1R132H), 28 nM (IDH1R132C), 6.14 µM (... |