Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Hydrocortisone cypionate is a corticosteroid ester and synthetic glucocorticoid corticosteroid.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | 5 days | $ 140.00 |
Description | Hydrocortisone cypionate is a corticosteroid ester and synthetic glucocorticoid corticosteroid. |
In vitro | Hydrocortisone treatment of dendritic cells (DCs) not only inhibits the production of IFN-γ but also prompts a rise in IL-4 release without affecting IL-5 levels. It mitigates postischemic oxidative stress, reduces perfusion pressure, and lowers transudate formation while preventing the postischemic release of syndecan-1, heparan sulfate, hyaluronan, and histamine from resident mast cells. At a concentration of 50 nM, hydrocortisone displays a dose-dependent reduction in GR transcript in hCMEC/D3 cells. Enhancing serum-reduced cell differentiation media with hydrocortisone significantly boosts the transendothelial electrical resistance (TER) across the hCMEC/D3 monolayer. Additionally, hydrocortisone-treated DCs exhibit suppressed expression of MHC II molecules, CD86, CD83, and a marked decrease in IL-12 secretion, showcasing its broad immunomodulatory effects. |
Molecular Weight | 486.64 |
Formula | C29H42O6 |
CAS No. | 508-99-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 125 mg/mL (256.86 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Hydrocortisone cypionate 508-99-6 Others inhibitor inhibit