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Homocarnosine

Catalog No. T32098   CAS 3650-73-5
Synonyms: NSC-92522, NSC92522, L-Homocarnosine, NSC 92522

Homocarnosine is an endogenous dipeptide in cerebral regions and cerebrospinal fluid.

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Homocarnosine Chemical Structure
Homocarnosine, CAS 3650-73-5
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Homocarnosine is an endogenous dipeptide in cerebral regions and cerebrospinal fluid.
Synonyms NSC-92522, NSC92522, L-Homocarnosine, NSC 92522
Molecular Weight 240.26
Formula C10H16N4O3
CAS No. 3650-73-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

TargetMolReferences and Literature

1. Huang J, Wang T, Yu D, Fang X, Fan H, Liu Q, Yi G, Yi X, Liu Q. l-Homocarnosine attenuates inflammation in cerebral ischemia-reperfusion injury through inhibition of nod-like receptor protein 3 inflammasome. Int J Biol Macromol. 2018 Jun 8. pii: S0141-8130(18)32623-0. doi: 10.1016/j.ijbiomac.2018.06.032. [Epub ahead of print] PubMed PMID: 29890246. 2. Sjaastad O, Blau N, Rydning SL, Peters V, Rødningen O, Stray-Pedersen A, Krossnes B, Tallaksen C, Koht J. Homocarnosinosis: A historical update and findings in the SPG11 gene. Acta Neurol Scand. 2018 May 6. doi: 10.1111/ane.12949. [Epub ahead of print] PubMed PMID: 29732542. 3. Kwiatkowski S, Kiersztan A, Drozak J. Biosynthesis of Carnosine and Related Dipeptides in Vertebrates. Curr Protein Pept Sci. 2018;19(8):771-789. doi: 10.2174/1389203719666180226155657. PubMed PMID: 29484990. 4. Elmaki EEA, Gong T, Nkonika DM, Wang G. Examining alterations in GABA concentrations in the basal ganglia of patients with Parkinson's disease using MEGA-PRESS MRS. Jpn J Radiol. 2018 Mar;36(3):194-199. doi: 10.1007/s11604-017-0714-z. Epub 2017 Dec 26. PubMed PMID: 29280067.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Enter the chemical formula of a compound to calculate its molar mass and elemental composition

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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Homocarnosine 3650-73-5 NSC-92522 NSC92522 L-Homocarnosine NSC 92522 inhibitor inhibit

 

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