store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
FR901464 (WB 2663B) is potent cytotoxic natural products that share an amine-containing tetrahydropyran ring.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 328.00 | |
5 mg | In stock | $ 788.00 | |
10 mg | In stock | $ 1,120.00 | |
25 mg | In stock | $ 1,660.00 | |
50 mg | In stock | $ 2,230.00 |
Description | FR901464 (WB 2663B) is potent cytotoxic natural products that share an amine-containing tetrahydropyran ring. |
In vitro | FR901464 (10-20 ng/ml; 6-24 hours) inhibited the growth of solid tumors, colon cancer, and methoxamine A fibrosarcoma in mice. FR901464 induced characteristic G1 and G2/M phase arrest in the cell cycle and internucleosomal degradation of genomic DNA in M-8 tumor cells by the same principle as SV40 promoter dependent cellular transcription. FR901464 (1-10 ng/ml) induced the transcription of some endogenous genes in M-8 cells, but did not inhibit the transcription of endogenous genes[1]. |
Synonyms | FR 901464, FR-901464, WB 2663B |
Molecular Weight | 507.62 |
Formula | C27H41NO8 |
CAS No. | 146478-72-0 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 90.0 mg/mL (177.3 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
FR901464 146478-72-0 Others FR 901464 FR-901464 WB 2663B inhibitor inhibit