Powder: -20°C for 3 years | In solvent: -80°C for 1 year
FM26 has a distinct isoxazole chemotype and effectively reduces IL-17a mRNA production in EL4 cells. FM26 is a potent and allosteric retinoic acid receptor-related orphan receptor γt (RORγt) inverse agonists with an IC50 of 264 nM.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 8-10 weeks | $ 1,970.00 | |
50 mg | 8-10 weeks | $ 2,580.00 | |
100 mg | 8-10 weeks | $ 3,400.00 |
Description | FM26 has a distinct isoxazole chemotype and effectively reduces IL-17a mRNA production in EL4 cells. FM26 is a potent and allosteric retinoic acid receptor-related orphan receptor γt (RORγt) inverse agonists with an IC50 of 264 nM. |
Targets&IC50 | RORγt:264 nM |
In vitro | FM26 ( 10 μM, 24h) significantly reduces IL-17a mRNA expression 27-fold in EL4 cells. |
Molecular Weight | 461.82 |
Formula | C22H15ClF3N3O3 |
CAS No. | 2407981-35-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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FM26 2407981-35-3 Metabolism ROR FM-26 FM 26 inhibitor inhibit