Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Dehydroevodiamine (DHE), a natural compound isolated from Evodia rutaecarpa, can inhibit AChE. It has hypotensive and neuroprotective effects and modulates nitric oxide production.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 39.00 | |
10 mg | In stock | $ 57.00 | |
25 mg | In stock | $ 90.00 | |
50 mg | In stock | $ 132.00 | |
100 mg | In stock | $ 195.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 54.00 |
Description | Dehydroevodiamine (DHE), a natural compound isolated from Evodia rutaecarpa, can inhibit AChE. It has hypotensive and neuroprotective effects and modulates nitric oxide production. |
In vivo | Dehydroevodiaminehydrochloride has strong protective effects against cognitive impairments through its antioxidant activity and inhibition of neurotoxicity and intracellular calcium. Thus, DHED may be an important therapeutic agent for memory-impaired symptoms. |
Animal Research | The effects of dehydroevodiamine·HCl (DHED) on cognitive improvement and the related mechanism in memory-impaired rat models, namely, a scopolamine-induced amnesia model and a Aβ1-42-infused model. The cognitive effects of DHED were measured using a water maze test and a passive avoidance test in the memory-impaired rat models. The results demonstrate that DHED (10 mg/kg, p.o.) and Donepezil (1 mg/kg, p.o.) ameliorated the spatial memory impairment in the scopolamine-induced amnestic rats. |
Source |
Molecular Weight | 337.8 |
Formula | C19H16ClN3O |
CAS No. | 111664-82-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 37 mg/mL (109.53 mM)
You can also refer to dose conversion for different animals. More
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Dehydroevodiamine hydrochloride 111664-82-5 Neuroscience AChE inhibit Inhibitor Dehydroevodiamine Hydrochloride Dehydroevodiamine inhibitor