Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DM1-(PEG)4-DBCO is a drug-linker conjugate that combines the potent microtubulin inhibitor mertansine (DM1) with the DBCO-PEG4-Ahx linker for the development of antibody-drug conjugates (ADCs). This conjugation aims to mitigate the systemic toxicity associated with maytansine while improving tumor-specific delivery, leveraging DM1’s capabilities as an antibody-conjugatable maytansinoid.
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100 mg | Inquiry | Inquiry | |
500 mg | Inquiry | Inquiry |
Description | DM1-(PEG)4-DBCO is a drug-linker conjugate that combines the potent microtubulin inhibitor mertansine (DM1) with the DBCO-PEG4-Ahx linker for the development of antibody-drug conjugates (ADCs). This conjugation aims to mitigate the systemic toxicity associated with maytansine while improving tumor-specific delivery, leveraging DM1’s capabilities as an antibody-conjugatable maytansinoid. |
Molecular Weight | 1198.79 |
Formula | C63H80ClN5O16 |
CAS No. | T17832 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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DM1-PEG4-DBCO T17832 Others DM-1-PEG4-DBCO DM1 PEG4 DBCO DM1PEG4DBCO inhibitor inhibit