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DL-threo-2-methylisocitrate sodium

Catalog No. T19291 CAS T19291

DL-threo-2-methylisocitrate is a substrate of isocitrate lyase 1 (ICL1). Using Michaelis-Menten nonlinear least squares fitting, kcat value was 5.24 s-1, the Km of the purified recombinant ICL1 of threonine-D(s)L(s)-isocitrate (ICA) was 188 μM. The Km of DL-threo-2-methylisocitrate (MICA) is approximately four times higher at 718 μM, and the kcat is 1.25 s-1.

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DL-threo-2-methylisocitrate sodium Chemical Structure

DL-threo-2-methylisocitrate sodium, CAS T19291

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Molecular Weight	544.19
Formula	C14H14Na6O14
CAS No.	T19291

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Gould TA, et al. Dual role of isocitrate lyase 1 in the glyoxylate and methylcitrate cycles in Mycobacterium tuberculosis. Mol Microbiol. 2006 Aug;61(4):940-7.

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Keywords

DL-threo-2-methylisocitrate sodium T19291 Others DLthreo2methylisocitrate sodium DL threo 2 methylisocitrate sodium inhibitor inhibit

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