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Compound 1T-0219 (SC)

Catalog No. T9545 CAS 383147-92-0

Compound 1T-0219 (SC) is a blocker of Akt1-FAK interaction reducing the stimulation of FAK phosphorylation in response to extracellular pressure in human SW620 colon cancer cells without affecting basal FAK phosphorylation.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Compound 1T-0219 (SC) Chemical Structure

Compound 1T-0219 (SC), CAS 383147-92-0

Pack Size	Availability	Price/USD
1 mg	In stock	$ 148.00
5 mg	In stock	$ 336.00
10 mg	In stock	$ 497.00
25 mg	In stock	$ 793.00
50 mg	In stock	$ 1,130.00

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Purity: 98%

Biological Description

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Description

Compound 1T-0219 (SC) is a blocker of AKT1-FAK interaction reducing the stimulation of FAK phosphorylation in response to extracellular pressure in human SW620 colon cancer cells without affecting basal FAK phosphorylation.

Molecular Weight	413.38
Formula	C20H19N3O7
CAS No.	383147-92-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 2 years

Solubility Information

DMSO: <10 mg/mL (24.19 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. More SK, Vomhof-Dekrey EE, Basson MD. ZINC4085554 inhibits cancer cell adhesion by interfering with the interaction of Akt1 and FAK. Oncol Lett. 2019 Jun;17(6):5251-5260. doi: 10.3892/ol.2019.10192. Epub 2019 Mar 27. PMID: 31186741; PMCID: PMC6507311.

Related compound libraries

This product is contained In the following compound libraries：

Cytoskeletal Signaling Pathway Compound Library Bioactive Compounds Library Max Anti-Colorectal Cancer Compound Library Anti-Cancer Compound Library Angiogenesis related Compound Library PPI Inhibitor Library Bioactive Compound Library Inhibitor Library

Related Products

Related compounds with same targets

2119738-71-3 Defactinib hydrochloride PF-03814735 5α-Hydroxycostic acid FAK inhibitor 2 Excisanin A Conteltinib Masitinib

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Keywords

Compound 1T-0219 (SC) 383147-92-0 Angiogenesis Cytoskeletal Signaling Tyrosine Kinase/Adaptors FAK Compound 1T 0219 (SC) Compound 1T0219 (SC) inhibitor inhibit

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