Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ceanothic acid derivatives show cytotoxic effect against OVCAR-3 and HeLa cancer cell lines.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | Inquiry | $ 2,450.00 | |
1 mL * 10 mM (in DMSO) | Inquiry | $ 2,998.00 |
Description | Ceanothic acid derivatives show cytotoxic effect against OVCAR-3 and HeLa cancer cell lines. |
In vitro | Six ceanothane and 1-norceanothane derivatives (1, 2, 8-11) were prepared from Ceanothic acid dibenzyl ester. These ring-A homologues of betulinic acid exhibited cytotoxic effects. Among these, 1-decarboxy-3-oxo-Ceanothic acid (2) was found to be the most cytotoxic against OVCAR-3 and HeLa cancer cell lines, with an IC50 of 2.8 and 6.6 microg/mL, respectively, and an IC50 of 11.3 microg/mL against normal cell line FS-5. |
Source |
Molecular Weight | 486.693 |
Formula | C30H46O5 |
CAS No. | 21302-79-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Ceanothic acid 21302-79-4 Others inhibitor inhibit