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CP21R7

Catalog No. T3684 CAS 125314-13-8

Synonyms: CP21

CP21R7 (CP21) is an effective and specific GSK3β inhibitor. It is used as an activator of stem cells prior to the induction of differentiation of stem cells to smooth muscle and endothelial cells. CP21R7 can be combined with BMP4 to commit human pluripotent stem cells to a mesodermal fate.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

CP21R7, CAS 125314-13-8

Pack Size	Availability	Price/USD
1 mg	In stock	$ 57.00
2 mg	In stock	$ 78.00
5 mg	In stock	$ 98.00
10 mg	In stock	$ 157.00
25 mg	In stock	$ 287.00
50 mg	In stock	$ 487.00
100 mg	In stock	$ 713.00
1 mL * 10 mM (in DMSO)	In stock	$ 74.00

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Purity: 98.21%

Purity: 96.14%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	CP21R7 (CP21) is an effective and specific GSK3β inhibitor. It is used as an activator of stem cells prior to the induction of differentiation of stem cells to smooth muscle and endothelial cells. CP21R7 can be combined with BMP4 to commit human pluripotent stem cells to a mesodermal fate.
Targets&IC50	PKCα:1900 nM., GSK-3β:1.8 nM

Synonyms	CP21
Molecular Weight	317.34
Formula	C19H15N3O2
CAS No.	125314-13-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

Ethanol: 1 mg/mL (3.15 mM)

DMSO: 59 mg/mL (185.9 mM)

H2O: < 1 mg/mL (insoluble or slightly soluble)

References and Literature

1. Gong L, et al. Bioorg Med Chem Lett. 2010 Mar 1;20(5):1693-6. 2. Sahara M, et al. Cell Res. 2015 Jan;25(1):148. 3. Patsch C, et al. Nat Cell Biol. 2015 Aug;17(8):1994-12003. 4. Sahara M, et al. Cell Res. 2014 Jul;24(7):820-41.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Kinase Inhibitor Library TGF-beta/Smad Compound Library Anti-Neurodegenerative Disease Compound Library Anti-Breast Cancer Compound Library Anti-Aging Compound Library Anti-Lung Cancer Compound Library Wnt/Hedgehog/Notch Compound Library Bioactive Compound Library HIF-1 Signaling Pathway Compound Library

Related Products

Related compounds with same targets

VX-11e GSK3β inhibitor II TBB 9-Hydroxycanthin-6-one 3F8 Kaempferol 3-neohesperidoside GSK-3 Inhibitor XIII GSK-3β inhibitor 2

Dose Conversion

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
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The answer of 19.713 mg appears in the Mass box

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

CP21R7 125314-13-8 Chromatin/Epigenetic Cytoskeletal Signaling PI3K/Akt/mTOR signaling Stem Cells GSK-3 PKC CP 21 Glycogen synthase kinase 3 Inhibitor CP-21 Glycogen synthase kinase-3 CP-21R7 CP21 inhibit inhibitor

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.