Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CP 316311 is a specific CRF1 receptor antagonist with potential antidepressant activity and may be used in the study of depression.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 293.00 | |
5 mg | In stock | $ 533.00 | |
10 mg | In stock | $ 683.00 | |
25 mg | In stock | $ 928.00 | |
50 mg | In stock | $ 1,260.00 | |
100 mg | In stock | $ 1,680.00 |
Description | CP 316311 is a specific CRF1 receptor antagonist with potential antidepressant activity and may be used in the study of depression. |
Targets&IC50 | CRF1 receptor:6.8 nM |
In vitro | CP-316311 is a CRF1 receptor antagonist that completely antagonizes CRF-stimulated adenylyl cyclase activity in rat cortex and endogenously expressed human CRF1 receptors in IMR32 cells[1]. |
In vivo | CP-316311 (3.2 mg/kg) demonstrates oral efficacy in central nervous system (CNS) models in vivo, blocking the effects of exogenous and endogenous CRF in rodent CNS models[1]. |
Molecular Weight | 327.46 |
Formula | C21H29NO2 |
CAS No. | 175139-41-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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CP 316311 175139-41-0 GPCR/G Protein CRFR CP-316311 CP316311 inhibitor inhibit