Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CL2A is a pH-sensitive, cleavable PEG8- and triazole-containing PABC-peptide-mc linker, characterized by its ability to induce a bystander effect. It forms a disulfide bond with an antibody at a cysteine residue. Labetuzumab govitecan utilizes this linker for its drug conjugation[1].
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Description | CL2A is a pH-sensitive, cleavable PEG8- and triazole-containing PABC-peptide-mc linker, characterized by its ability to induce a bystander effect. It forms a disulfide bond with an antibody at a cysteine residue. Labetuzumab govitecan utilizes this linker for its drug conjugation[1]. |
Molecular Weight | 1106.22 |
Formula | C51H79N9O18 |
CAS No. | 1846605-04-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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CL2A 1846605-04-6 Others CL-2A inhibitor inhibit