Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CDK12-IN-3 is a selective CDK12 inhibitor (IC50: 491 nM in an enzymatic assay).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | CDK12-IN-3 is a selective CDK12 inhibitor (IC50: 491 nM in an enzymatic assay). |
Targets&IC50 | CDK12:491 nM |
In vitro | CDK12-IN-3 is a selective CDK12 inhibitor that is profiled across a panel of 352 kinases at 0.1 μM. CDK12-IN-3 shows potent inhibition of phosphorylation of Ser2 on the CTD repeat domain of RNA Pol II. It also shows growth inhibition of OV90 cells and acute cytotoxicity to THP1 cells. |
Molecular Weight | 470.52 |
Formula | C23H28F2N8O |
CAS No. | 2220184-50-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
CDK12-IN-3 2220184-50-7 Cell Cycle/Checkpoint CDK CDK12IN3 CDK12 IN 3 CDK-12-IN-3 inhibitor inhibit