Powder: -20°C for 3 years | In solvent: -80°C for 2 years
CDK12-IN-3 is a selective CDK12 inhibitor (IC50: 491 nM in an enzymatic assay).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | 5 days | $ 148.00 |
Description | CDK12-IN-3 is a selective CDK12 inhibitor (IC50: 491 nM in an enzymatic assay). |
Targets&IC50 | CDK12:491 nM |
In vitro | CDK12-IN-3 is a selective CDK12 inhibitor that is profiled across a panel of 352 kinases at 0.1 μM. CDK12-IN-3 shows potent inhibition of phosphorylation of Ser2 on the CTD repeat domain of RNA Pol II. It also shows growth inhibition of OV90 cells and acute cytotoxicity to THP1 cells. |
Molecular Weight | 470.52 |
Formula | C23H28F2N8O |
CAS No. | 2220184-50-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 2 years
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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CDK12-IN-3 2220184-50-7 Cell Cycle/Checkpoint CDK CDK12IN3 CDK12 IN 3 CDK-12-IN-3 inhibitor inhibit