Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CBK289001 is a tartrate-resistant acid phosphatase (TRAP/ACP5) inhibitor. CBK289001 inhibits TRAP 5b MV , TRAP 5b OX and TRAP 5a OX with IC 50 s of 125 μM, 4.21 μM and 14.2 μM, respectively.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | Inquiry | $ 970.00 |
Description | CBK289001 is a tartrate-resistant acid phosphatase (TRAP/ACP5) inhibitor. CBK289001 inhibits TRAP 5b MV , TRAP 5b OX and TRAP 5a OX with IC 50 s of 125 μM, 4.21 μM and 14.2 μM, respectively. |
In vitro | CBK289001 exclusively impedes TRAP3-mediated high cell migration in a dose-dependent manner, demonstrating significant migration inhibition starting 24 hours post-treatment and achieving reduced migration velocity over 30 hours at concentrations of 20 μM or 100 μM. This indicates CBK289001 effectively hinders TRAP-dependent migration in TRAP-overexpressing MDA-MB-231 breast cancer cells. |
Molecular Weight | 396.4 |
Formula | C19H20N6O4 |
CAS No. | 1212663-24-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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CBK289001 1212663-24-5 CBK-289001 CBK 289001 inhibitor inhibit