Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CAY10770 is an inhibitor of the cytochrome P450 (CYP) isoform CYP4Z1 (IC50= 5.9 μM).1It is selective for CYP4Z1 over CYP4A11, CYP4F2, CYP4F3a, CYP4F3b (IC50s = 187-282 μM) but does inhibit CYP4F8 and CYP4F12 (IC50s = 167 and 91 μM, respectively). CAY10770 (3 μM) inhibits the production of 14(15)-EET, 19-HETE, and 14(15)-DiHET by 83, 86, and 80%, respectively, in T47D breast cancer cells expressing CYP4Z1.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
250 μg | 35 days | $ 155.00 | |
500 μg | 35 days | $ 288.00 | |
1 mg | 35 days | $ 540.00 |
Description | CAY10770 is an inhibitor of the cytochrome P450 (CYP) isoform CYP4Z1 (IC50= 5.9 μM).1It is selective for CYP4Z1 over CYP4A11, CYP4F2, CYP4F3a, CYP4F3b (IC50s = 187-282 μM) but does inhibit CYP4F8 and CYP4F12 (IC50s = 167 and 91 μM, respectively). CAY10770 (3 μM) inhibits the production of 14(15)-EET, 19-HETE, and 14(15)-DiHET by 83, 86, and 80%, respectively, in T47D breast cancer cells expressing CYP4Z1. |
Synonyms | CAY10770 |
Molecular Weight | 276.33 |
Formula | C14H20N4O2 |
CAS No. | 2428734-45-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Chloroform: 10 mg/mL
Methyl Acetate: 1 mg/mL
Ethanol: 1 mg/mL
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CAY10770 2428734-45-4 CAY 10770 CAY-10770 inhibitor inhibit