Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Bim-BLK-A efficiently blocks Bim-induced apoptosis after Bax is activated on the mitochondria. The cellular target of Bim-BLK-A was identified to be the succinate dehydrogenase subunit B (SDHB) protein of complex II of the mitochondrial electron transfer chain (ETC). Bim-BLK-A protects the integrity of the ETC and allows treated cells to continue to proliferate after apoptosis induction.
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Description | Bim-BLK-A efficiently blocks Bim-induced apoptosis after Bax is activated on the mitochondria. The cellular target of Bim-BLK-A was identified to be the succinate dehydrogenase subunit B (SDHB) protein of complex II of the mitochondrial electron transfer chain (ETC). Bim-BLK-A protects the integrity of the ETC and allows treated cells to continue to proliferate after apoptosis induction. |
Synonyms | Bim Blocker A, Compound A, Bim BLK A, BimBLKA |
Molecular Weight | 469.44 |
Formula | C20H18F3N3O5S |
CAS No. | T26817 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Bim-BLK-A T26817 Bim Blocker A Compound A Bim BLK A BimBLKA inhibitor inhibit