store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Benzquinamide (P2647), an antiemetic agent with anticancer activity, inhibits p-glycoprotein-mediated drug efflux and potentiates the cytotoxicity of anticancer drugs in multidrug-resistant cells.The Ki values of Benzquinamide for α2A, α2B, and α2C adrenergic receptor (α2-AR) were 1,365, 691, and 545 nM, respectively. 545 nM, respectively.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 700.00 | |
5 mg | In stock | $ 1,800.00 |
Description | Benzquinamide (P2647), an antiemetic agent with anticancer activity, inhibits p-glycoprotein-mediated drug efflux and potentiates the cytotoxicity of anticancer drugs in multidrug-resistant cells.The Ki values of Benzquinamide for α2A, α2B, and α2C adrenergic receptor (α2-AR) were 1,365, 691, and 545 nM, respectively. 545 nM, respectively. |
Targets&IC50 | α2C:545 nM (Ki), α2B:691 nM (Ki), α2A:1,365 nM (Ki) |
Synonyms | BZQ, P2647, Benzoquinamide |
Molecular Weight | 404.5 |
Formula | C22H32N2O5 |
CAS No. | 63-12-7 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Benzquinamide 63-12-7 GPCR/G Protein Neuroscience Adrenergic Receptor P-2647 P 2647 BZQ P2647 Benzoquinamide inhibitor inhibit