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BMS 180742

Catalog No. T25164 CAS 138828-04-3

Synonyms: BMS-180742, BMS180742

BMS 180742 is an exosite inhibitor of thrombin.

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BMS 180742, CAS 138828-04-3

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25 mg	Inquiry	$ 1,520.00

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Biological Description

Chemical Properties

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Description

BMS 180742 is an exosite inhibitor of thrombin.

Synonyms	BMS-180742, BMS180742
Molecular Weight	1404.52
Formula	C67H93N11O22
CAS No.	138828-04-3

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Schumacher WA, Steinbacher TE, Heran CL, Seiler SM, Michel IM, Ogletree ML. Comparison of thrombin active site and exosite inhibitors and heparin in experimental models of arterial and venous thrombosis and bleeding. J Pharmacol Exp Ther. 1993 Dec;267(3):1237-42. PubMed PMID: 8263785. 2. Tesfamariam B, Allen GT, Normandin D, Antonaccio MJ. Involvement of the "tethered ligand" receptor in thrombin-induced endothelium-mediated relaxations. Am J Physiol. 1993 Nov;265(5 Pt 2):H1744-9. PubMed PMID: 8238588. 3. Webb ML, Taylor DS, Molloy CJ. Effects of thrombin receptor activating peptide on phosphoinositide hydrolysis and protein kinase C activation in cultured rat aortic smooth muscle cells: evidence for "tethered-ligand" activation of smooth muscle cell thrombin receptors. Biochem Pharmacol. 1993 Apr 22;45(8):1577-82. PubMed PMID: 8387299. 4. Seiler SM, Michel IM, Fenton JW 2nd. Involvement of the "tethered-ligand" receptor in thrombin inhibition of platelet adenylate cyclase. Biochem Biophys Res Commun. 1992 Feb 14;182(3):1296-302. PubMed PMID: 1371679.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

BMS 180742 138828-04-3 BMS-180742 BMS180742 inhibitor inhibit

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