Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Azido-PEG4-Val-Cit-PAB-OH is a 4-unit PEG ADC linker and a PEG-based PROTAC linker. It is employed for the synthesis of antibody-drug conjugates (ADCs)[1] and PROTACs[2].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | 5 days | $ 30.00 |
Description | Azido-PEG4-Val-Cit-PAB-OH is a 4-unit PEG ADC linker and a PEG-based PROTAC linker. It is employed for the synthesis of antibody-drug conjugates (ADCs)[1] and PROTACs[2]. |
In vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
Molecular Weight | 652.75 |
Formula | C29H48N8O9 |
CAS No. | 2055024-64-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Azido-PEG4-Val-Cit-PAB-OH 2055024-64-9 Others AzidoPEG4ValCitPABOH Azido PEG4 Val Cit PAB OH Azido-PEG-4-Val-Cit-PAB-OH inhibitor inhibit