Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Azido-PEG4-C2-acid, a PEG-based PROTAC linker, is utilized in the synthesis of vRucaparib-TP4. It serves as a non-cleavable 4 unit PEG ADC linker for antibody-drug conjugate (ADC) synthesis.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 5 days | $ 38.00 | |
50 mg | 5 days | $ 52.00 | |
100 mg | 5 days | $ 85.00 |
Description | Azido-PEG4-C2-acid, a PEG-based PROTAC linker, is utilized in the synthesis of vRucaparib-TP4. It serves as a non-cleavable 4 unit PEG ADC linker for antibody-drug conjugate (ADC) synthesis. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
Molecular Weight | 291.3 |
Formula | C11H21N3O6 |
CAS No. | 1257063-35-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Azido-PEG4-C2-acid 1257063-35-6 Others Azido PEG4 C2 acid AzidoPEG4C2acid Azido-PEG-4-C2-acid inhibitor inhibit