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Antibacterial agent 122

Catalog No. T60690 CAS 109310-99-8

Antibacterial agent 122 (compound 15) is a thiourea derivative that can be used in the studies of tuberculosis. Antibacterial agent 122 shows low cytotoxicity as well as anti-mycobacterial activity [1].

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Antibacterial agent 122 Chemical Structure

Antibacterial agent 122, CAS 109310-99-8

Pack Size	Availability	Price/USD
25 mg	6-8 weeks	$ 1,520.00
50 mg	6-8 weeks	$ 1,980.00
100 mg	6-8 weeks	$ 2,500.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

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Description

In vitro

Antibacterial agent 122 (compound 15) (25-200 μM, 24 h) inhibits M. tuberculosis H37Rv with the MIC 50 value of 5.9 μM and inhibits NO production in LPS-stimulated RAW 264.7 cell cultures with an IC 50 value of 8.1μM [1]. Antibacterial agent 122 (compound 15) (25-200 μM) acts on NO scavenging with an IC 50 value of 184.2 μM, and almost completely inhibits iNOS expression in LPS-stimulated RAW264.7 macrophages at a concentration of 100 μM [1]. Antibacterial agent 122 (compound 15) (0-200 μM, 24 h) inhibits TNF-α and IL-1β production in LPS-stimulated macrophages with the IC 50 values of 28.4 μM and 47.9 μM, respectively [1]. Antibacterial agent 122 (compound 15) (25-100 μM, 4 days) inhibits M. tuberculosis M299 with an MIC 50 value of 24.7 μM [1].

Molecular Weight	302.35
Formula	C15H14N2O3S
CAS No.	109310-99-8

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Powder: -20°C for 3 years | In solvent: -80°C for 1 year

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Antibacterial agent 122 109310-99-8 inhibitor inhibit

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