Shopping Cart

Your shopping cart is currently empty

Ampicillin sodium

Name: Ampicillin sodium
Brand: TargetMol
SKU: T6386
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

😃Good

Catalog No. T6386Cas No. 69-52-3

Alias Penialmen, Domicillin, D-(-)-α-Aminobenzylpenicillin sodium salt, Citteral

Ampicillin sodium (Domicillin) is a broad-spectrum β -lactam antibiotic. Ampicillin sodium combates a variety of Gram-positive and Gram-negative bacteria.

Ampicillin sodium

😃Good

Purity: 99.26%

Catalog No. T6386Alias Penialmen, Domicillin, D-(-)-α-Aminobenzylpenicillin sodium salt, CitteralCas No. 69-52-3

Ampicillin sodium (Domicillin) is a broad-spectrum β -lactam antibiotic. Ampicillin sodium combates a variety of Gram-positive and Gram-negative bacteria.

Pack Size	Price	USA Warehouse	Global Warehouse
1 g	$35	In Stock	In Stock
2 g	$48	In Stock	In Stock
5 g	$73	-	In Stock
10 g	$113	-	In Stock
25 g	$187	-	In Stock
50 g	$278	-	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.26%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Ampicillin sodium (Domicillin) is a broad-spectrum β -lactam antibiotic. Ampicillin sodium combates a variety of Gram-positive and Gram-negative bacteria.
Targets&IC50	HEK293 cells:> 100 μM (CC50), carnitine/carnitine antiport:7.6 mM, transporter:9.9 mM (Ki), enzyme transpeptidase:1.8 µg/mL
In vitro	METHODS: After treating porcine Escherichia coli with Ampicillin sodium (0.1, 1, 2.5, 5, 10 μg/mL), E.M.B was observed. The number of viable Escherichia coli on the culture medium. RESULTS: Ampicillin inhibited the growth of porcine Escherichia coli in a dose-dependent manner. The effective inhibitory concentration of Ampicillin is 2.5 μg/mL. [1]
In vivo	METHODS: To study the antibacterial effect of Ampicillin sodium, Ampicillin (0.2 mL/20 g) was orally or subcutaneously injected into mice. RESULTS: The efficacy of Ampicillin in treating most infections is significantly better than that of Epicillin and Amoxycillin. [2] METHODS: To study the neuroprotective effect of Ampicillin sodium, Ampicillin sodium (200 mg/kg) was intraperitoneally injected into a mouse model of transient anterior cerebral ischemia. RESULTS: Ampicillin sodium can significantly reduce hippocampal cell death, lower the activity of matrix metalloproteinases (MMP), and increase the expression of glutamate transporter-1 (GLT-1). [3]
Synonyms	Penialmen, Domicillin, D-(-)-α-Aminobenzylpenicillin sodium salt, Citteral

Chemical Properties

Molecular Weight	371.39
Formula	C₁₆H₁₈N₃NaO₄S
Cas No.	69-52-3
Smiles	[Na+].CC1(C)SC2C(NC(=O)C(N)c3ccccc3)C(=O)N2C1C([O-])=O
Relative Density.	no data available

Storage & Solubility Information

Storage

In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 68 mg/mL (183.1 mM), Sonication is recommended.

Ethanol: 69 mg/mL (185.79 mM), Sonication is recommended.

DMSO: 270 mg/mL (727 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 5 mg/mL (13.46 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

H2O/Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6926 mL	13.4629 mL	26.9259 mL	134.6294 mL
5 mM	0.5385 mL	2.6926 mL	5.3852 mL	26.9259 mL
10 mM	0.2693 mL	1.3463 mL	2.6926 mL	13.4629 mL
20 mM	0.1346 mL	0.6731 mL	1.3463 mL	6.7315 mL
50 mM	0.0539 mL	0.2693 mL	0.5385 mL	2.6926 mL
100 mM	0.0269 mL	0.1346 mL	0.2693 mL	1.3463 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc