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Amastatin hydrochloride

Catalog No. T19665 CAS 100938-10-1

Synonyms: BIMI-1803, Amastatin HCl, ZX-AFC000547, ZXAFC000547, BIMI1803, J-000280, J000280

Amastatin HCl is an inhibitor of aminopeptidase. It also induces vasoconstriction.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Amastatin hydrochloride Chemical Structure

Amastatin hydrochloride, CAS 100938-10-1

Pack Size	Availability	Price/USD
500 μg	35 days	$ 83.00
1 mg	35 days	$ 150.00
5 mg	35 days	$ 475.00
10 mg	35 days	$ 870.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Amastatin HCl is an inhibitor of aminopeptidase. It also induces vasoconstriction.

Synonyms	BIMI-1803, Amastatin HCl, ZX-AFC000547, ZXAFC000547, BIMI1803, J-000280, J000280
Molecular Weight	511.01
Formula	C21H39ClN4O8
CAS No.	100938-10-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: Soluble

References and Literature

1. Kawabata A, Kinoshita M, Nishikawa H, Kuroda R, Nishida M, Araki H, Arizono N, Oda Y, Kakehi K. The protease-activated receptor-2 agonist induces gastric mucus secretion and mucosal cytoprotection. J Clin Invest. 2001 Jun;107(11):1443-50. PubMed PMID: 11390426; PubMed Central PMCID: PMC209315. 2. Kawabata A, Oono Y, Yonezawa D, Hiramatsu K, Inoi N, Sekiguchi F, Honjo M, Hirofuchi M, Kanke T, Ishiwata H. 2-Furoyl-LIGRL-NH2, a potent agonist for proteinase-activated receptor-2, as a gastric mucosal cytoprotective agent in mice. Br J Pharmacol. 2005 Jan;144(2):212-9. PubMed PMID: 15655521; PubMed Central PMCID: PMC1575994. 3. Gee NS, Kenny AJ. Proteins of the kidney microvillar membrane. Enzymic and molecular properties of aminopeptidase W. Biochem J. 1987 Aug 15;246(1):97-102. PubMed PMID: 2890346; PubMed Central PMCID: PMC1148244. 4. Kawabata A, Nishikawa H, Saitoh H, Nakaya Y, Hiramatsu K, Kubo S, Nishida M, Kawao N, Kuroda R, Sekiguchi F, Kinoshita M, Kakehi K, Arizono N, Yamagishi H, Kawai K. A protective role of protease-activated receptor 1 in rat gastric mucosa. Gastroenterology. 2004 Jan;126(1):208-19. PubMed PMID: 14699501.

Dose Conversion

You can also refer to dose conversion for different animals. More

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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The answer of 19.713 mg appears in the Mass box

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Amastatin hydrochloride 100938-10-1 ZX-AFC-000547 Amastatin Hydrochloride BIMI 1803 BIMI-1803 Amastatin HCl ZX-AFC000547 ZXAFC 000547 ZXAFC000547 BIMI1803 J-000280 ZX-AFC 000547 J 000280 ZXAFC-000547 J000280 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.