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Alpha-Hederin

Catalog No. T3368 CAS 27013-91-8

Synonyms: Helixin, Tauroside E, α-Hederin, Hederoside C

Alpha-Hederin (Tauroside E) is a water-soluble pentacyclic triterpenoid saponin found in the seeds of Nigella sativa, with hemolytic and apoptotic properties.

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Alpha-Hederin, CAS 27013-91-8

Pack Size	Availability	Price/USD	Quantity
20 mg	In stock	$ 130.00
1 mL * 10 mM (in DMSO)	In stock	$ 81.00

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Purity: 99.83%

Purity: 99.44%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Alpha-Hederin (Tauroside E) is a water-soluble pentacyclic triterpenoid saponin found in the seeds of Nigella sativa, with hemolytic and apoptotic properties.
Kinase Assay	For affinity determination, Nuciferine is subjected to primary radioligand binding assays tested at a single 10 μM concentration to displace 50% of the radioligand at a given receptor target. If a more than 50% of the radioligand is displaced, Nuciferine is selected for a secondary binding assay tested at 11 concentrations in triplicate in competition with the radioligand to generate an IC50 and Ki. Binding assays are performed in 96-well plates with 125 μL per well in appropriate binding buffer using radioligand at or near the Kd. Plates are incubated at room temperature in the dark for 90 min. Reactions are stopped by vacuum filtrations onto 0.3% polyethyleneimine soaked 96-well filter mats using a 96-well Filtermate harvester, followed by at least three washes of cold wash buffer. Scintillation cocktail is melted onto dried filters and radioactivity is counted using a Wallac Trilux Microbeta[1].
Source	Natural Products > Araliaceae > Aralia

Synonyms	Helixin, Tauroside E, α-Hederin, Hederoside C
Molecular Weight	750.96
Formula	C41H66O12
CAS No.	27013-91-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 133.2 mM

References and Literature

1. Randhawa MA, et al. Am J Chin Med. 2011;39(6):1075-91. ; 2. Fallahi M, et al. Avicenna J Phytomed. 2016 Jan-Feb;6(1):77-85.

Related compound libraries

This product is contained In the following compound libraries：

Traditional Chinese Medicine Monomer Library Anti-Cancer Active Compound Library Antiparasitic Natural Product Library Bioactive Compound Library Mitochondria-Targeted Compound Library Natural Product Library for HTS Anti-Tumor Natural Product Library FDA-Approved & Pharmacopeia Drug Library NO PAINS Compound Library Chinese Pharmacopoeia Natural Product Library

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Keywords

Alpha-Hederin 27013-91-8 Apoptosis Others a-Hederin Helixin Tauroside E Alpha Hederin Inhibitor α-Hederin alpha-Hederin Hederoside C AlphaHederin inhibit inhibitor

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