keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ACT-462206 is an orally available Orexin 1/Orexin 2 receptor antagonist that crosses the blood-brain barrier.ACT-462206 is highly potent and can be used in studies of sleep and anxiety.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 37.00 | |
5 mg | In stock | $ 85.00 | |
10 mg | In stock | $ 139.00 | |
25 mg | In stock | $ 293.00 | |
50 mg | In stock | $ 469.00 | |
100 mg | In stock | $ 745.00 | |
500 mg | In stock | $ 1,490.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 94.00 |
Description | ACT-462206 is an orally available Orexin 1/Orexin 2 receptor antagonist that crosses the blood-brain barrier.ACT-462206 is highly potent and can be used in studies of sleep and anxiety. |
In vivo | In male Wistar rats, ACT-462206 (0, 10, 30, 100, 300 mg/kg; oral gavage; single dose) decreased the duration of the first non-rapid eye movement (NREM) sleep episode (60 seconds) and the first rapid eye movement (REM) sleep episode (30 seconds). Furthermore, ACT-462206 dose-dependently reduced total wake time and behavioral home cage activity, while increasing both REM and NREM sleep durations[1]. |
Molecular Weight | 388.48 |
Formula | C20H24N2O4S |
CAS No. | 1361321-96-1 |
keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 80 mg/mL (205.93 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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ACT-462206 1361321-96-1 GPCR/G Protein Neuroscience OX Receptor ACT462206 ACT 462206 inhibitor inhibit