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4-amino-1,8-Naphthalimide

Catalog No. T21524 CAS 1742-95-6

4-amino-1,8-Naphthalimide (4-ANI) is a PARP inhibitor with IC50 of 180 nM

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4-amino-1,8-Naphthalimide, CAS 1742-95-6

Pack Size	Availability	Price/USD
10 mg	In stock	$ 42.00
25 mg	In stock	$ 91.00
50 mg	In stock	$ 148.00
100 mg	In stock	$ 238.00
200 mg	In stock	$ 353.00
1 mL * 10 mM (in DMSO)	In stock	$ 48.00

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Purity: 95.13%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

4-amino-1,8-Naphthalimide (4-ANI) is a PARP inhibitor with IC50 of 180 nM

Molecular Weight	212.2
Formula	C12H8N2O2
CAS No.	1742-95-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 2 years

Solubility Information

DMSO: 3.6 mg/mL (16.96 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. SCHLICKER, A. 4-Amino-1,8-naphthalimide: a novel inhibitor of poly(ADP-ribose) polymerase and radiation sensitizer[J]. International Journal of Radiation Biology, 1999, 75(1):91-100.

Related compound libraries

This product is contained In the following compound libraries：

Human Metabolite Library Anti-Cancer Compound Library Anti-Cardiovascular Disease Compound Library Epigenetics Compound Library Inhibitor Library Anti-Ovarian Cancer Compound Library Anti-Prostate Cancer Compound Library Bioactive Compounds Library Max DNA Damage & Repair Compound Library NO PAINS Compound Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

4-amino-1,8-Naphthalimide 1742-95-6 Chromatin/Epigenetic DNA Damage/DNA Repair PARP Inhibitor 4amino1,8Naphthalimide 4-Aminonaphthalimide inhibit poly ADP ribose polymerase 4 amino 1,8 Naphthalimide inhibitor

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