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2,2-Dihydroxyacetic acid

Name: 2,2-Dihydroxyacetic acid
Brand: TargetMol
SKU: T4843
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T4843Cas No. 563-96-2

Alias Glyoxylic acid monohydrate, Formylformic acid

2,2-Dihydroxyacetic acid (Formylformic acid) is an intermediate in the glyoxalate cycle, which enables certain organisms to convert fatty acids to carbohydrates.2,2-Dihydroxyacetic acid has been found to be associated with primary hyperoxaluria, an inborn error of metabolism. As an aldehyde, glyoxalate is also highly active and can modify proteins to form advanced glycosylation products (AGEs).

2,2-Dihydroxyacetic acid

🥰Excellent

Purity: 99.25%

Catalog No. T4843Alias Glyoxylic acid monohydrate, Formylformic acidCas No. 563-96-2

Pack Size	Price	Availability	Quantity
10 g	$29	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock

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Purity:99.25%

Resource Download

COA GC HNMR

Product Introduction

Bioactivity

Description	2,2-Dihydroxyacetic acid (Formylformic acid) is an intermediate in the glyoxalate cycle, which enables certain organisms to convert fatty acids to carbohydrates.2,2-Dihydroxyacetic acid has been found to be associated with primary hyperoxaluria, an inborn error of metabolism. As an aldehyde, glyoxalate is also highly active and can modify proteins to form advanced glycosylation products (AGEs).
Synonyms	Glyoxylic acid monohydrate, Formylformic acid

Chemical Properties

Molecular Weight	92.05
Formula	C₂H₄O₄
Cas No.	563-96-2
Smiles	C(C(O)=O)(O)O
Relative Density.	1.33 g/mL at 20°C

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 25 mg/mL (271.59 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (21.73 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	10.8637 mL	54.3183 mL	108.6366 mL	543.1831 mL
5 mM	2.1727 mL	10.8637 mL	21.7273 mL	108.6366 mL
10 mM	1.0864 mL	5.4318 mL	10.8637 mL	54.3183 mL
20 mM	0.5432 mL	2.7159 mL	5.4318 mL	27.1592 mL
50 mM	0.2173 mL	1.0864 mL	2.1727 mL	10.8637 mL
100 mM	0.1086 mL	0.5432 mL	1.0864 mL	5.4318 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc