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(+/-)-Pinocembrin

Name: (+/-)-Pinocembrin
Brand: TargetMol
SKU: TN2077
Price: 35 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN2077Cas No. 68745-38-0

Alias NSC 43318, (±)-5,7-Dihydroxyflavanone

(+/-)-Pinocembrin (NSC-43318), a natural product from axillary pines, is a GPR120 ligand that promotes wound healing in the HaCaT cell line.

(+/-)-Pinocembrin

🥰Excellent

Purity: 99.79%

Catalog No. TN2077Alias NSC 43318, (±)-5,7-DihydroxyflavanoneCas No. 68745-38-0

(+/-)-Pinocembrin (NSC-43318), a natural product from axillary pines, is a GPR120 ligand that promotes wound healing in the HaCaT cell line.

Pack Size	Price	Availability
1 mg	$35	In Stock
5 mg	$81	In Stock
10 mg	$129	In Stock
25 mg	$219	In Stock
50 mg	$326	In Stock
100 mg	$485	In Stock
200 mg	$693	In Stock

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Purity:99.79%

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COA HPLC HNMR

Product Introduction

Bioactivity

Description	(+/-)-Pinocembrin (NSC-43318), a natural product from axillary pines, is a GPR120 ligand that promotes wound healing in the HaCaT cell line.
In vitro	(+/-)-Pinocembrin exhibits wound-healing properties (EC50=0.07 µM), potentially engaging additional mechanisms beyond the activation of GPR120.[1]
Synonyms	NSC 43318, (±)-5,7-Dihydroxyflavanone

Chemical Properties

Molecular Weight	256.25
Formula	C₁₅H₁₂O₄
Cas No.	68745-38-0
Smiles	O=C1C=2C(OC(C1)C3=CC=CC=C3)=CC(O)=CC2O
Relative Density.	1.386 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (195.12 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 5 mg/mL (19.51 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.9024 mL	19.5122 mL	39.0244 mL	195.1220 mL
5 mM	0.7805 mL	3.9024 mL	7.8049 mL	39.0244 mL
10 mM	0.3902 mL	1.9512 mL	3.9024 mL	19.5122 mL
20 mM	0.1951 mL	0.9756 mL	1.9512 mL	9.7561 mL
50 mM	0.0780 mL	0.3902 mL	0.7805 mL	3.9024 mL
100 mM	0.0390 mL	0.1951 mL	0.3902 mL	1.9512 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc