Powder: -20°C for 3 years | In solvent: -80°C for 1 year
β-Secretase Inhibitor IV is a potent, cell-active inhibitor of BACE-1(IC50s of 15.6 and 16.3nM under BACE-1 concentrations of 2 nM and 100 pM, respectively).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
500 μg | 35 days | $ 335.00 | |
1 mg | 35 days | $ 633.00 | |
5 mg | 35 days | $ 2,480.00 |
Description | β-Secretase Inhibitor IV is a potent, cell-active inhibitor of BACE-1(IC50s of 15.6 and 16.3nM under BACE-1 concentrations of 2 nM and 100 pM, respectively). |
Targets&IC50 | Cathepsin D:7620±210 nM , BACE1:15.3±0.6 nM , BACE2:230±26 nM |
In vitro | β-Secretase Inhibitor IV (Compound 2) inhibits the production of Aβ peptides with an EC50 of 43 nM in the cell culture assay. β-Secretase Inhibitor IV potently suppresses the secretion of sAPP_NF and EV40 from HEK293T cells(IC50 : 30 nM). |
Molecular Weight | 578.72 |
Formula | C31H38N4O5S |
CAS No. | 797035-11-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
β-Secretase Inhibitor IV 797035-11-1 Others beta-Secretase Inhibitor IV βSecretase Inhibitor IV b-Secretase Inhibitor IV β Secretase Inhibitor IV inhibitor inhibit