Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Alpha-Chaconine has anti-inflammatory effect, associated with the suppression of AP-1, and supports its possible therapeutic role for the treatment of sepsis. Alpha-Chaconine also has cytotoxic effects.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | Inquiry | $ 580.00 | |
1 mL * 10 mM (in DMSO) | Inquiry | $ 890.00 |
Description | Alpha-Chaconine has anti-inflammatory effect, associated with the suppression of AP-1, and supports its possible therapeutic role for the treatment of sepsis. Alpha-Chaconine also has cytotoxic effects. |
In vitro | This study confirmed their synergistic cytotoxic effects on C6 rat glioma cells by three different cell viability tests, namely WST-1 (water-soluble tetrazolium) assay sensitive to intracellular NADH concentration, menadione-catalysed chemiluminescent assay depending on both NAD(P)H concentration and NAD(P)H:quinone reductase activity, and LDH (lactate dehydrogenase) assay sensitive to the release of LDH from damaged cells. The maximum cytotoxic effect was observed at a ratio of 1:1 between α±-solanine and alpha-Chaconine at micromolar concentrations. |
Source |
Synonyms | alpha-Chaconine |
Molecular Weight | 852.06 |
Formula | C45H73NO14 |
CAS No. | 20562-03-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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α-Chaconine 20562-03-2 Cell Cycle/Checkpoint DNA Damage/DNA Repair Immunology/Inflammation Neuroscience IL Receptor COX DNA/RNA Synthesis αChaconine a-Chaconine alpha-Chaconine α Chaconine α-Chaconine inhibitor inhibit