(S,R,S)-AHPC-C10-NH2

Name: (S,R,S)-AHPC-C10-NH2
Brand: TargetMol
SKU: T17881
Rating: 4.5 (1 reviews)

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Catalog No. T17881Cas No. 2341796-74-3

Alias VH032-C10-NH2

(S,R,S)-AHPC-C10-NH2 (VH032-C10-NH2) is a synthesized E3 ligase ligand-linker conjugate, comprising an (S,R,S)-AHPC-based VHL ligand and a linker, designed for BET-targeted PROTAC applications.

(S,R,S)-AHPC-C10-NH2

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Catalog No. T17881Alias VH032-C10-NH2Cas No. 2341796-74-3

(S,R,S)-AHPC-C10-NH2 (VH032-C10-NH2) is a synthesized E3 ligase ligand-linker conjugate, comprising an (S,R,S)-AHPC-based VHL ligand and a linker, designed for BET-targeted PROTAC applications.

Pack Size	Price	Availability
1 mg	$51	Backorder
5 mg	$97	Backorder
10 mg	$143	Backorder
25 mg	$236	Backorder
50 mg	$347	Backorder
100 mg	$517	Backorder

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Product Introduction

Bioactivity

Description	(S,R,S)-AHPC-C10-NH2 (VH032-C10-NH2) is a synthesized E3 ligase ligand-linker conjugate, comprising an (S,R,S)-AHPC-based VHL ligand and a linker, designed for BET-targeted PROTAC applications.
In vitro	PROTACs comprise two distinct ligands joined by a linker: one ligand binds to an E3 ubiquitin ligase, and the other targets the specific protein. Utilizing the intracellular ubiquitin-proteasome system, PROTACs facilitate the selective degradation of target proteins [2].
Synonyms	VH032-C10-NH2

Chemical Properties

Molecular Weight	613.85
Formula	C₃₃H₅₁N₅O₄S
Cas No.	2341796-74-3
Smiles	C([C@@H](NC(CCCCCCCCCCN)=O)[C@](C)(C)C)(=O)N1[C@H](C(NCC2=CC=C(C=C2)C3=C(C)N=CS3)=O)C[C@@H](O)C1
Relative Density.	1.156 g/cm3 (Predicted)

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Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

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