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(S)-(-)-5-Fluorowillardiine hydrochloride

Catalog No. T13480L CAS 1321546-70-6

Synonyms: (S)-5-Fluorowillardiine hydrochloride, (5S)-Fluorowillardiine hydrochloride

(S)-(-)-5-Fluorowillardiine hydrochloride is a potent and specific agonist of AMPAR.

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(S)-(-)-5-Fluorowillardiine hydrochloride Chemical Structure

(S)-(-)-5-Fluorowillardiine hydrochloride, CAS 1321546-70-6

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2 mg	5 days	$ 72.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

(S)-(-)-5-Fluorowillardiine hydrochloride is a potent and specific agonist of AMPAR.

Synonyms	(S)-5-Fluorowillardiine hydrochloride, (5S)-Fluorowillardiine hydrochloride
Molecular Weight	253.62
Formula	C7H9ClFN3O4
CAS No.	1321546-70-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 6.67 mg/mL (26.30 mM), Sonication is recommended.

References and Literature

1. Hawkinson JE, et al. Effects of thiocyanate and AMPA receptor ligands on (S)-5-fluorowillardiine, (S)-AMPA and (R,S)-AMPA binding. Eur J Pharmacol. 1997 Jun 25;329(2-3):213-21. 2. Kessler M, et al. Use of [3H]fluorowillardiine to study properties of AMPA receptor allosteric modulators. Brain Res. 2006 Mar 3;1076(1):25-41. 3. Rembach A, et al. Antisense peptide nucleic acid targeting GluR3 delays disease onset and progression in the SOD1 G93A mouse model of familial ALS. J Neurosci Res. 2004 Aug 15;77(4):573-82.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

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