Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(3S, 4S)-PF-06459988 is the less active S enantiomer of PF-06459988, which is a potent irreversible inhibitor of T790M mutant epidermal growth factor receptor (EGFR). PF-06459988 exhibits excellent selectivity against EGFR wild-type due to its minimally reactive electrophile, which reduces the likelihood of off-target labeling.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | 5 days | $ 82.00 |
Description | (3S, 4S)-PF-06459988 is the less active S enantiomer of PF-06459988, which is a potent irreversible inhibitor of T790M mutant epidermal growth factor receptor (EGFR). PF-06459988 exhibits excellent selectivity against EGFR wild-type due to its minimally reactive electrophile, which reduces the likelihood of off-target labeling. |
Molecular Weight | 431.88 |
Formula | C19H22ClN7O3 |
CAS No. | 1858291-14-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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(3S,4S)-PF-06459988 1858291-14-1 (3S,4S)PF06459988 PF 06459988 (3S,4S) PF 06459988 PF-06459988 PF06459988 inhibitor inhibit